5-Methyl-2'-deoxycytidine-5'-Triphosphate - (N-2026)
5-Methyl-dCTP
$72.00
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N-2026
Description
5-Methyl-2'-deoxycytidine is an important epigenetic modification. This modification can be incorporated into DNA via PCR with Taq polymerase and 5-Methyl-2'-deoxycytidine-5'-Triphosphate for epigenetics studies. It has also been shown that microinjection or electroporation of 5-Methyl-2'-deoxycytidine-5'-Triphosphate has been shown to lead to developmental arrest in many cell lines.
Product details
| Catalog No | N-2026 |
|---|---|
| Purity | ≥95% by AX-HPLC |
| Extinction Coefficient | 8,900 Lmol-1cm-1 at 278 nm |
| Molecular Formula | C10H18N3O13P3 (free acid) |
| Molecular Weight | 481.10 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | 5-Methyl-dCTP |
| Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Cytidine |
| Sugar Type(s) | DNA |
| Nucleotide Category | Base Modified DNA |
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Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.
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References
- Kamiya, Hiroyuki; Iida, Emiko; Murata-Kamiya, Naoko; Yamamoto, Yoshihiro; Miki, Takeyoshi; Harashima, Hideyoshi . Suppression of spontaneous and hydrogen peroxide-induced mutations by a MutT-type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 protein
- Wong, K. K.; Markillie, L. M.; Saffer, J. D. . A novel method for producing partial restriction digestion of DNA fragments by PCR with 5-methyl-CTP.
- Kutyavin, Igor V. . Use of Base-Modified Duplex-Stabilizing Deoxynucleoside 5′-Triphosphates To Enhance the Hybridization Properties of Primers and Probes in Detection Polymerase Chain Reactionâ€ÂÂ
- Schildberg, Frank A.; Hagmann, Cristina A.; Böhnert, Volker; Tolba, René H. . Improved transplantation outcome by epigenetic changes.
- Jiang, Wenjing; Wu, Linni; Duan, Junling; Yin, Huanshun; Ai, Shiyun . Ultrasensitive electrochemiluminescence immunosensor for 5-hydroxymethylcytosine detection based on Fe(3)O(4)@SiO(2) nanoparticles and PAMAM dendrimers.
- Wang, Q;Yin, H;Zhou, Y;Cao, L;Yu, Z;Xu, Y;Ai, S; . Photoelectrochemical biosensor for 5?formylcytosine based on WS 2 /Bi/ Bi 2 O 2 CO 3 nanocomposite and rolling circle amplification
