5-Nitro-1-indolyl-2'-deoxyribose-5'-Triphosphate - (N-2031)
5-Nitro-1-Indolyl-drTP
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N-2031
Product details
| Catalog No | N-2031 |
|---|---|
| Purity | ≥90% by AX-HPLC |
| Extinction Coefficient | 21,735 Lmol-1cm-1 at 265 nm |
| Molecular Formula | C13H17N2O14P3 (free acid) |
| Molecular Weight | 518.20 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | 5-Nitro-1-Indolyl-drTP |
| Application | Mutagenesis |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Thymidine, Uridine |
| Sugar Type(s) | DNA |
| Nucleotide Category | Base Modified DNA |
Technical documents
N-2031 Safety Data Sheet
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References
- Brown, Jessica A.; Fowler, Jason D.; Suo, Zucai . Kinetic Basis of Nucleotide Selection Employed by a Protein Template-Dependent DNA Polymerase
- Zahn, Karl E.; Belrhali, Hassan; Wallace, Susan S.; Doublié, Sylvie . Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
- Reineks, Edmunds Z.; Berdis, Anthony J. . Evaluating the contribution of base stacking during translesion DNA replication.
- Brown, Jessica A.; Pack, Lindsey R.; Sherrer, Shanen M.; Kshetry, Ajay K.; Newmister, Sean A.; Fowler, Jason D.; Taylor, John-Stephen; Suo, Zucai . Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ.
