8-Oxo-2'-deoxyguanosine

8-Oxo-dG
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This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order or contact us to speak with a customer service representative.

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Product Details

OLIGObuilder Code {8O-dG}
Other Name(s) 8-Oxo-dG
Base Analog(s) Guanosine
Application Epigenetics/DNA Damage, Mutagenesis
Oligo Modification Type DNA Purines (A or G) Analog


References

Sanders, Laurie H.; Devadoss, Babho; Raja, Geraldine V.; O'Connor, Jaime; Su, Shengchang; Wozniak, Daniel J.; Hassett, Daniel J.; Berdis, Anthony J.; Sutton, Mark D. . Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.

Clark, Tyson A.; Spittle, Kristi E.; Turner, Stephen W.; Korlach, Jonas . Direct detection and sequencing of damaged DNA bases.

De Bont, Rinne; van Larebeke, Nik . Endogenous DNA damage in humans: a review of quantitative data.

Kohen, Ron; Nyska, Abraham . Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification.

Maki, H.; Sekiguchi, M. . MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis.

Lee, B. M.; Jang, J. J.; Kim, H. S. . Benzo[a]pyrene diol-epoxide-I-DNA and oxidative DNA adducts associated with gastric adenocarcinoma.

Musarrat, J.; Arezina-Wilson, J.; Wani, A. A. . Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis.

Okamoto, K.; Toyokuni, S.; Uchida, K.; Ogawa, O.; Takenewa, J.; Kakehi, Y.; Kinoshita, H.; Hattori-Nakakuki, Y.; Hiai, H.; Yoshida, O. . Formation of 8-hydroxy-2'-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma.

Boiteux, S.; Radicella, J. P. . The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis.

Bohr, Vilhelm A.; Stevnsner, Tinna; de Souza-Pinto, Nadja C. . Mitochondrial DNA repair of oxidative damage in mammalian cells.

Fortini, P.; Parlanti, E.; Sidorkina, O. M.; Laval, J.; Dogliotti, E. . The type of DNA glycosylase determines the base excision repair pathway in mammalian cells.

Nishimura, Susumu . Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.

Preston, Thomas J.; Henderson, Jeffrey T.; McCallum, Gordon P.; Wells, Peter G. . Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs.

Lagadu, Stéphanie; Lechevrel, Mathilde; Sichel, François; Breton, Jean; Pottier, Didier; Couderc, Rémy; Moussa, Fathi; Prevost, Virginie . 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST.