8-Oxoguanosine-5'-Triphosphate - (N-1066)
8-Oxo-GTP
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N-1066
Product details
| Catalog No | N-1066 |
|---|---|
| Purity | ≥90% by AX-HPLC |
| Extinction Coefficient | 7,868 Lmol-1cm-1 at 296 nm |
| Molecular Formula | C10H16N5O15P3 (free acid) |
| Molecular Weight | 539.10 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | 8-Oxo-GTP |
| Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Guanosine |
| Sugar Type(s) | RNA |
| Nucleotide Category | Base Modified RNA |
Technical documents
N-1066 Safety Data Sheet
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Certificate of analysis
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Intellectual property
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References
- Bolin, Celeste; Cardozo-Pelaez, Fernando . Assessing biomarkers of oxidative stress: analysis of guanosine and oxidized guanosine nucleotide triphosphates by high performance liquid chromatography with electrochemical detection.
- Zhang, Li-Qun; Dai, Da-Peng; Gan, Wei; Takagi, Yasumitsu; Hayakawa, Hiroshi; Sekiguchi, Mutsuo; Cai, Jian-Ping . Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells.
- Sastre-Moreno, Guillermo; Sánchez, Arancha; Esteban, Verónica; Blanco, Luis . ATP insertion opposite 8-oxo-deoxyguanosine by Pol4 mediates error-free tolerance in Schizosaccharomyces pombe.
- Ordonez, Heather; Shuman, Stewart . Mycobacterium smegmatis DinB2 misincorporates deoxyribonucleotides and ribonucleotides during templated synthesis and lesion bypass.
- Bratulic, Sinisa; Toll-Riera, Macarena; Wagner, Andreas . Mistranslation can enhance fitness through purging of deleterious mutations.
- Nakamura, Akiyoshi; Wang, Daole; Komatsu, Yasuo . Molecular mechanism of substrate recognition and specificity of tRNA(His) guanylyltransferase during nucleotide addition in the 3'-5' direction.
