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Research Update

Transient Expression of Modified TERT mRNA Extends Telomeres and Opens Door for Therapy

Scientists may have uncovered a novel way to cure disease and slow aging through the transient expression of telomerase reverse transcriptase (TERT), a protein that elongates chromosomes.

Since replication machinery cannot copy to the very ends of DNA, chromosomes get shorter with each cellular division. Sections of repetitive DNA, called telomeres, have evolved to protect the ends of chromosomes. As these molecular caps shorten, the cell enters into replicative senescence which is often followed by cell death. While this “molecular clock” is necessary for maintaining healthy tissue and organs, this process is thought to play a role in aging and is disrupted in a variety of diseases.

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Ask an Expert

What do GMP, ISO and QSR mean, and how do they differ?

GMP stands for Good Manufacturing Practices, and refers to a system of manufacturing that guarantees reproducibility of product quality to set specifications. cGMP is simply Current Good Manufacturing Practices and refers to compliance with current regulations.

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Zone in with Zon Blog Post

Three Fascinating Facts about Epigenetics

  • You Are What Your Father Eats
  • Exercise Affects Epigenetics
  • There’s an Epigenetic Clock
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