Twitter Twitter Facebook Facebook Linked In Linked In Zone In Zone In Google Plus Zone In
 

Research Update

Transient Expression of Modified TERT mRNA Extends Telomeres and Opens Door for Therapy

Scientists may have uncovered a novel way to cure disease and slow aging through the transient expression of telomerase reverse transcriptase (TERT), a protein that elongates chromosomes.

Since replication machinery cannot copy to the very ends of DNA, chromosomes get shorter with each cellular division. Sections of repetitive DNA, called telomeres, have evolved to protect the ends of chromosomes. As these molecular caps shorten, the cell enters into replicative senescence which is often followed by cell death. While this “molecular clock” is necessary for maintaining healthy tissue and organs, this process is thought to play a role in aging and is disrupted in a variety of diseases.

Read More
 
News
TriLink to be Exclusive Manufacturer of Solulink Products
Featured Product
Modified Cas9 mRNA: Now available with pseudo-U and 5meC or pseudo-U.
New Poster
Have you seen our latest data? Our new CleanTag™ Ligation Kit for Small RNA Library Prep may handle inputs as low as 10 pg.
 
A Fast and Cost-Effective Approach To Therapeutic GMP Manufacturing

  We offer single-batch or multiple-batch synthesis for IND-enabling tox studies and early phase clinical studies. Because we don't require large scale synthesis, we can deliver your material quickly and at an affordable price. We provide drug substances plus supporting documentation to streamline the IND submission process and carry you through to clinical trials-saving you time and money.

Manufacturing of therapeutic grade material is available for:

 
  • mRNA
  • Long RNA
  • Oligonucleotides
  • Nucleotides & Nucleosides
  • Aptamers
Learn More

 
Ask an Expert

What do GMP, ISO and QSR mean, and how do they differ?

GMP stands for Good Manufacturing Practices, and refers to a system of manufacturing that guarantees reproducibility of product quality to set specifications. cGMP is simply Current Good Manufacturing Practices and refers to compliance with current regulations.

Read More

 
Zone in with Zon Blog Post

Three Fascinating Facts about Epigenetics

  • You Are What Your Father Eats
  • Exercise Affects Epigenetics
  • There’s an Epigenetic Clock
Read More

 
 

© 2015 TriLink BioTechnologies, Inc. | All Rights Reserved