CleanTag™ Small RNA-Seq Kits used to Identify Changes in miRNA that Link Gut Microbiota to Intestinal Cell Proliferation
The microbiome of the human gut is composed of a mix of microbiota, including bacteria, archaea, viruses and eukaryotic microbes. Changes in the gut microbiome (e.g. loss of diversity, or an abnormal proliferation a particular type of microbe) have been linked to a broad range of chronic, acute, and mood disorders, such as Crohn’s disease, asthma, depression, obesity, as well as some infections.
However, despite several links to various diseases, it is widely understood that these are just correlations, and the mechanisms of how the microbiota influence human physiology are still unclear.
Recently, a group from the University of North Carolina Chapel Hill published results from a study that sought to define the molecular mechanisms under which microbiota affect the body. In particular, they investigated the intestinal epithelial cells (IECs) of the jejunum, which includes a number of cell types, including differentiated ...