Methylphosphonate

MP
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This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order or contact us to speak with a customer service representative.

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Product Details

OLIGObuilder Code (mp)
Other Name(s) MP
Property Nuclease Stability
Oligo Modification Type Backbone


References

Agrawal, Sudhir; Goodchild, John . Oligodeoxynucleoside methylphosphonates: synthesis and enzymic degradation

Blake, K. R.; Murakami, A.; Spitz, S. A.; Glave, S. A.; Reddy, M. P.; Ts'o, P. O.; Miller, P. S. . Hybridization arrest of globin synthesis in rabbit reticulocyte lysates and cells by oligodeoxyribonucleoside methylphosphonates.

Kulka, M.; Smith, C. C.; Levis, J.; Fishelevich, R.; Hunter, J. C.; Cushman, C. D.; Miller, P. S.; Ts'o, P. O.; Aurelian, L. . Synergistic antiviral activities of oligonucleoside methylphosphonates complementary to herpes simplex virus type 1 immediate-early mRNAs 4, 5, and 1.

Miller, Paul S.; McParland, Kevin B.; Jayaraman, Krishna; Tso, Paul O. P. . Biochemical and biological effects of nonionic nucleic acid methylphosphonates

Miller, P. S.; Agris, C. H.; Aurelian, L.; Blake, K. R.; Murakami, A.; Reddy, M. P.; Spitz, S. A.; Ts'o, P. O. . Control of ribonucleic acid function by oligonucleoside methylphosphonates.

Strauss-Soukup, J. K.; Vaghefi, M. M.; Hogrefe, R. I.; Maher, L. J. . Effects of Neutralization Pattern and Stereochemistry on DNA Bending by Methylphosphonate Substitutions†

Trapane, Tina L.; Hogrefe, Richard I.; Reynolds, Mark A.; Kan, Lou-sing; Tso, Paul O. P. . Interstrand Complex Formation of Purine Oligonucleotides and Their Nonionic Analogs: The Model System of d(AG)8and Its Complement, d(CT)8†

Wickstrom, Eric; Bacon, Thomas A.; Wickstrom, Erica L. . Down-Regulation of c-MYC Antigen Expression in Lymphocytes of Eµ-c-myc Transgenic Mice Treated with Anti-c-myc DNA Methylphosphonates