N1-Methyladenosine-5'-Triphosphate - (N-1042)
|Purity||≥90% by AX-HPLC|
|Extinction Coefficient||14,600 Lmol-1cm-1 at 257 nm|
|Molecular Formula||C11H18N5O13P3 (free acid)|
|Molecular Weight||521.20 g/mole (free acid)|
|Recommended Storage||-20°C or below|
|Application||Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies|
|Nucleotide Category||Base Modified RNA|
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- Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
- Motorin, Yuri; Helm, Mark . RNA nucleotide methylation.
- Andries, Oliwia; Mc Cafferty, Séan; De Smedt, Stefaan C.; Weiss, Ron; Sanders, Niek N.; Kitada, Tasuku . N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice.