5-Methoxyuridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of 5-Methoxyuridine can reduce the immunogenicity of the resulting mRNA.
|Purity||≥95% by AX-HPLC|
|Extinction Coefficient||8,300 Lmol-1cm-1 at 278 nm|
|Molecular Formula||C10H17N2O16P3 (free acid)|
|Molecular Weight||514.10 g/mole (free acid)|
|Recommended Storage||-20°C or below|
|Other Name(s)||5-Methoxy-UTP, 5-moUTP|
|Application||Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies|
|Nucleotide Category||Base Modified RNA|
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Li, Bin; Zeng, Chunxi; Dong, Yizhou . Design and assessment of engineered CRISPR-Cpf1 and its use for genome editing.