N1-Methylpseudouridine-5'-Triphosphate, sodium salt, is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-Methylpseudouridine can reduce the immunogenicity of the resulting mRNA.
To learn more about TriLink's N1-Methylpseudouridine, visit https://www.trilinkbiotech.com/modified-nucleotides
| Catalog No | N-1081 |
|---|---|
| Purity | ≥99% by AX-HPLC |
| Extinction Coefficient | 8,877 Lmol-1cm-1 at 271 nm |
| Molecular Formula | C10H17N2O15P3 (free acid) |
| Molecular Weight | 498.10 g/mole (free acid) |
| Salt Form | Na+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | N1-Methylpseudouridine-5'-Triphosphate, N1meΨTP, m1ΨTP, 1-Methyl-PseudoUridine Phosphoramidite, N1-Methyl-Pseudouridine-5'-Triphosphate |
| Application | In vitro Transcription |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Pseudouridine |
| Sugar Type(s) | RNA |
| Nucleotide Category | Base Modified RNA |
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Svitkin, YV;Gingras, AC;Sonenberg, N; . Membrane-dependent relief of translation elongation
