2',3'-Dideoxyinosine-5'-Triphosphate - (N-4017)

ddITP, Didanosine triphosphate

This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.


2',3'-Dideoxyinosine-5'-Triphosphate (ddITP) is a sugar modified nucleoside triphosphate, where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. The inability of polymerases to extend from a dideoxy nucleotide causes the chain termination and is useful in a variety of biotechnology applications. ddITP is used in cycle sequencing, enzyme mechanistic studies and for producing RNA and DNA sequences that cannot be extended by polymerases or joined by DNA ligases. Another notable application that utilizes a primer terminated on the 3′ end with a dideoxy modification is pyrophosphorolysis-activated polymerization (PAP). This technique is valuable for the detection of rare mutations.

Product Details

Catalog No N-4017
Purity ≥90% by AX-HPLC
Extinction Coefficient 12,300 Lmol-1cm-1 at 248 nm
Molecular Formula C10H15N4O12P3 (free acid)
Molecular Weight 476.10 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) ddITP, Didanosine triphosphate
Application Aptamers
Backbone 5'-Triphosphate
Base Analog(s) Guanosine, Inosine
Nucleotide Category Sugar Modified

Technical Documents

Product FAQs

Certificate of Analysis

Intellectual Property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.